John J. Leddy, Ph.D.

Associate Professor, Department of Cellular and Molecular Medicine,
Faculty of Medicine, University of Ottawa,
451 Smyth Road, Ottawa, ON K1H 8M5
Office: 3141
Tel.: (613) 562-5800 (8170)
FAX: (613) 562-5434
Email: jleddy@uottawa.ca

Research Interests:

Dr. Leddy is an Assistant Professor in the Department of Cellular and Molecular Medicine and is Co-Director of Evaluations for the Faculty of Medicine. He obtained his Honours B.Sc. in Biochemistry and Ph.D. in Pharmacology from the University of Ottawa. In 1999, he completed his transition from laboratory research in pharmacology to a career in biomedical education. His research interests in medical education include the evaluation and assessment of courses in Medicine and the Biomedical Sciences, with a particular interest in pharmacology content. His research also extends to the investigation of outcomes of tools used in the admissions process at the Faculty of Medicine.

Awards:

Provincial:

2007 Ontario Leadership in Faculty Teaching Award

Local:

2008 Honorary President of the MEDS 2008 Graduating Class
2007 Honorary President of the MEDS 2007 Graduating Class
2006 Honorary President of the Aesculapian Society
2005 Canadian Association of Medical Education Merit Award
2005 Bristol-Myers Squibb Award for Excellence in Medical Teaching
2004 Honorary President of the MEDS 2004 Graduating Class
2003 Bristol-Myers Squibb Award for Excellence in Medical Teaching
2002 Bristol-Myers Squibb Award for Excellence in Medical Teaching
1990-95 Medical Research Council Studentship
1990 Governor General's Medal: University of Ottawa
1990 University of Ottawa Gold Medal: Faculty of Science

Selected references:

Abstract presentations:

Leddy, J.J., Moineau, G., Humphrey-Murto, S., Puddester, D., Wood, T.J. and Hébert, R.L.: Does an Emotional Intelligence Test Predict Admission to Medical School and Success During Medical Training. AFMC-CAME Conference, Victoria, BC, 2007.

Jalali, A., Sung, R., Obeidat, A., Hincke, M. and Leddy, J.J., Podcasting: a New Approach to Teaching Anatomy, 6 th Annual Merlot International Conference, Ottawa, Canada, 8-11 August, 2006.

Leddy, J.J ., Wood, T.J. and Hébert, R.L., Reliability and Predictive Value of the Autobiographical Sketch in the Admissions Process, 12th International Ottawa Conference on Clinical Competence, May 20-24 2006, New York, USA, p.248.

Leddy, J.J . Response Rates for Web-based Medical Student Evaluation of Teaching. 12th International Ottawa Conference on Clinical Competence, May 20-24 2006, New York, USA, p.275.

Refereed Publications:

Leddy, J.J. and Tuana, B.S.: Preparation of Cardiac Sarcoplasmic Reticulum, in Biochemical Techniques in the Heart, 1996, J.H. McNeill, ed., CRC Press, Chapter 1.

Singh P., Leddy J.J., Chatzis G.J., Salih M., Tuana B.S .: Alternative splicing generates a CaM kinase IIbeta isoform in myocardium that targets the sarcoplasmic reticulum through a putative alphaKAP and regulates GAPDH. Mol Cell Biochem .(2005) 270:215-21.

Singh P, Salih M, Leddy J.J., Tuana BS.: The muscle specific CaM kinase IIbetaM assembles with the glycolytic enzyme complex at the sarcoplasmic reticulum and modulates the activity of GAPDH in a Ca2+/calmodulin dependent manner. J Biol Chem (2004) 279 : 35176-82.

Meng, H., Leddy, J.J., Frank, J., Holland, P. and Tuana, B.S.: The Association of Cardiac Dystrophin with Myofibrils/Z-disc Regions in Cardiac Muscle Suggests a Novel Role in the Contractile Apparatus. J Biol Chem (1996) 271: 12364-12371.

Ray, A.R., Kyselovic, J., Leddy, J.J., Wigle, J.T., Jasmin, B.J. and Tuana, B.S.: Regulation of Dihydropyridine and Ryanodine Receptor Gene Expression in Skeletal Muscle. Role of nerve, protein kinase C and cAMP pathways. J Biol Chem (1995) 270: 25837-25844.

Kyselovic, J., Leddy, J.J., Ray, A., Wigle, J. and Tuana, B.S.: Temporal Differences in the Induction of Dihydropyridine Receptor Subunits and Ryanodine Receptors during Skeletal Muscle Development. J Biol Chem (1994) 269: 21770-21777.

Leddy, J.J. , Murphy, B.J., Yi, Q., Doucet, J.-P., Pratt, C. and Tuana, B.S.: A 60 kDa Calmodulin Binding Polypeptide of Skeletal Muscle Sarcoplasmic Reticulum is a Calmodulin-Dependent Protein Kinase that Associates with and Phosphorylates Several Membrane Proteins. Biochem J (1993) 295: 849-856.

Surewicz, W.K., Leddy, J.J. and Mantsch, H.H.: Structure, Stability and Receptor Interaction of Cholera Toxin As Studied by Fourier-Transform Infrared Spectroscopy. Biochemistry (1990), 29: 8106-8111.